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A new way to reduce weight and reduce diabetes without reducing calories



The prevalence of diabetes and obesity drives many individuals to try to lose weight by dieting - but low-calorie diets are difficult to maintain at many. New research published in the Journal of Physiology suggests that reducing the consumption of specific building blocks of proteins (amino acids) may resist metabolic problems that occur in diabetes and obesity.
Researchers at the University of Wisconsin-Madison found that lowering the consumption of specific types of amino acids (called branched chain amino acids (BCCA)) improved metabolic health, even when total calories were not reduced.
Importantly, the mice in this study ate significantly and therefore did not experience calorie reduction in general. Despite continuing to eat a high-fat and high-sugar diet, mice experienced an improvement in metabolic health.

If these results can be translated into humans, it is possible that such diets, or drugs that mimic the effect of a low diet in some BCCA amino acids, would be easier to follow and more effective than conventional diets that determine calorie consumption.

The research team predicts that a reduced diet in the said amino acids can be an effective way to treat or prevent metabolic syndrome, which includes high blood pressure, high blood sugar, abnormal cholesterol levels, excess abdominal fat and risk of diabetes, Heart disease, stroke.

Dudley Lamming, one of the lead researchers in the study, commented on the findings:

“We have identified an unexpected role for BCCA in regulating energy balance, and we show that a diet with low levels of BCCA promotes tendency and good control of blood sugar. Our results also suggest that the specific amino acid composition of dietary protein - not just how much protein we eat - regulates metabolic health. ”

Full Study:
Cummings, NE, Williams, EM, Kasza, I., Konon, EN, Schaid, MD, Schmidt, BA, Poudel, C., Sherman, DS, Yu, D., Arriola Apelo, SI, Cottrell, SE, Geiger, G., Barnes, ME, Wisinski, JA, Fenske, RJ, Matkowskyj, KA, Kimple, ME, Alexander, CM, Merrins, MJ and Lamming, DW (2017), Restoration of metabolic health by reduced consumption of branched-chain amino acids. J Physiol. doi: 10.1113 / JP275075
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